dot与microct双模式成像算法分析word格式论文.docxVIP

AbstractDiffuse optical tomography(DOT) is a kind of high depth biomedical imaging technology which make use of scattered photons to detect the tissue with merit of low cost and no radiation damage, hence it is outstanding in the disease diagnosis, pharmaceutical research, monitoring pathology progression and therapies and other biomedical research fields. However, the inverse problem of DOT is ill-posed and non-linear due to the diffusive nature of the photons inside the biological tissue, which leads to a poor spatial resolution. Multi-modality imaging method can improve its spatial resolution.In this paper, we present a triangle mesh generation method from CT images, which uses an adaptive boundary sampling algorithm to convert the image of CT into a planar straight line graph and mesh it with Delaunay method firstly. Then we refine the initial mesh by edge subdivision method and relax and smooth the mesh to improve its quality at last. Nodes and elements are labeled during the mesh generation and revised by a revising algorithm.We present an image reconstruction method for DOT and micro-CT double modality imaging system. The method is based on diffuse approximation, and takes use of finite element method(FEM) to solve steady-state diffuse equation, Newton type method to reconstruct the optical coefficients and Laplace regularization to incorporate the structural priori information. The simulations show that the incorporation of structural priori information improves the quality of DOT greatly.Key words: Diffuse optical tomographyDouble-modality imaging Finite element method目录摘要 .................................................................................................................. IAbstract................................................................................................................II1绪论1.1生物医学成像技术概述 ..........................................................................(1)1.2扩散光学断层成像 ...........................................