l733060对子宫内膜癌细胞的影响-effects of l 733060 on endometrial carcinoma cells.docxVIP

下载本文档

3
0
约4.7万字
约 48页
2018-05-28 发布于上海
举报
版权申诉

l733060对子宫内膜癌细胞的影响-effects of l 733060 on endometrial carcinoma cells.docx

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

l733060对子宫内膜癌细胞的影响-effects of l 733060 on endometrial carcinoma cells

目录中文摘要············································································································1英文摘要············································································································4英文缩写············································································································8研究论文L-733060对子宫内膜癌细胞的影响前言············································································································9材料与方法······························································································10结果··········································································································15附图··········································································································17附表··········································································································19讨论··········································································································22结论··········································································································26参考文献··································································································27综述NK-1受体及其拮抗剂在肿瘤中的应用··············································31附录··················································································································45致谢··················································································································46个人简历··········································································································47L-733060对子宫内膜癌细胞的影响摘要目的：子宫内膜癌是最常见的女性生殖系统恶性肿瘤之一。近年来随着人口老龄化、人口增长、人口体重增加，子宫内膜癌的发病率逐年增加。全球每年大约有320,000名女性被诊断为子宫内膜癌。尽管子宫内膜癌以I期最为常见，并且采用手术治疗后5年生存率可达到85-90%，但对于III–IV期的女性患者即使规范化的手术、放疗及化疗联合治疗后，其5年生存率仅为30-40%。联合化疗可以提高晚期及复发患者的无瘤生存期，但并不提高其总生存时间。美国最近的调查表明其子宫内膜癌五年生存率大约81.8%，每年有近4489名II–IV期子宫内膜癌患者死亡，而在发展中国家仅仅为67%。因此新型抗肿瘤药物有待探究。NK-1受体即神经激肽-1受体，是鸟嘌呤核苷酸结合蛋白偶联受体超家族成员之一，