脑梗死急性期优化治疗方案临床研究-clinical study on optimized treatment scheme of acute cerebral infarction.docx

成都中医药大学博士学位论文 成都中医药大学博士学位论文 PAGE PAGE 4 Abstract Objective： Study the influence of optimized treatment program integrated Traditional Chinese Medicine(TCM) and western medicine on acute cerebral infarction patients. Methods： observe the change of TCM syndrome score， NIHSS， BI and mRS score at the position of pre-treatment， 14 days after treatment， 28 days after treatment and 90 days， through two kinds of treatment means include Western medicine therapy with ZFXN oral preparation and simple Western medicine treatment on acute cerebral infarction patients. Results： (1) mortality rate： the number of death patients with acute cerebral infarction do not exist significant difference between two group. (2) TCM disease severity of symptoms ： the effect of reduction of TCM symptoms in ZFXN group does not exist statistically significan compare with the Western medicine group. (3) Impact on life of TCM symptoms ： ZFXN group points compared with Western medicine group in the treatment of 28 days were statistically significant ， ZFXN group less than the Western medicine group. (4) modified Rankin score： ZFXN Group and Western Group mRS show no significant difference at 14 days， treatment 28 days and 90 days. (5) NIHSS score： ZFXN group’s NIHSS score in 28 days show statistically significant with Western medicine group on NIHSS score. (6) life ability： there’s no statistical significance between two group when 14 days，28 days and 90 days on BI. (7) Security evaluation: there’s no obviously laboratory test data exchange after take the ZFXN preparation. Conclusion： (1) ZFXN preparation can not reduce mortality in cerebral infarction patients than Western medicine therapy； (2) The effect of reducing severity of disease symptoms of ZFXN therapy is stronger than Western medicine therapy； (3) ZFXN therapy improve the neurological deficits in cerebral infarction patients is better than Western medicine group. (4) ZFXN preparation is convient, safe and efficient for ac