中药二黄散对伴有HPV感染CINⅠ患者宫颈组织T―betGATA3影响.docVIP

中药二黄散对伴有HPV感染的CINⅠ患者宫颈组织T―bet、GATA3的影响 　　【摘要】目的探讨壮医药线点灸配合疏肝健脾方治疗肝硬化腹水的临床治疗效果。方法选取2012年1月至2013年12月收治住院并且辨证属于肝郁气滞，脾胃失调型的60例肝硬化腹水患者作为观察对象，随机分为对照组30例，以疏肝健脾方+西药常规药物进行治疗；观察组30例，在对照组治疗基础上加用壮医药线点灸配合治疗。两组患者治疗2周为一个疗程。3个月后对比观察两组患者的治疗效果。比较两组患者治疗前后主要自觉症状（腹胀、乏力、胁痛、纳差等）改善时间；治疗前后腹围、肝功能（ALT、AST、ALB、TBil、A/G）以及凝血酶原时间的变化情况。结果两组治疗效果比较差异有统计学意义（P0.05），观察组治疗效果明显优于对照组。治疗后，两组患者自觉症状评分均显著改善（P0.01），观察组患者自觉症状评分改善更明显（P0.01）。两组患者的腹围均显著改善（P0.01），观察组患者的腹围改善更明显（P0.01）。治疗后，两组患者的肝功能（ALT、AST、ALB）均显著改善（P001），观察组患者改善更明显（P0.01）。治疗后，观察组的凝血酶原时间较对照组显著改善（P0.01）。结论壮医药线点灸配合疏肝健脾方治疗肝硬化腹水可明显提高临床疗效，可行性较高，值得推广。 　　【关键词】壮医药线点灸；疏肝健脾方；肝硬化腹水 　　中图分类号：R752.5+2文献标识码：ADOI：10.3969/j.issn2015.06.000 　　【Abstract】ObjectiveTo investigate Medicated Thread Moxibustion Treatment Shuganjianpi clinical treatment of liver cirrhosis.Methods60 cases of ascites due to cirrhosis-who were admitted to hospital from January，2012 to December，2013 diagnosing with liver qi stagnation，spleen and stomach disorders-were observed.They were randomly divided into control group and observation group with 30 cases in each group.The control group were treated with method of soothing liver and strengthening spleen + conventional western medicine，and based on which the observation group were added MTMZ.Two weeks were taken as one course of treatment in both groups.After treating for three months，therapeutic effects were compared and observed between groups.In addition，time for improvement of main subjective symptoms（abdominal distension，lack of strength，hypochondriac pain and poor appetite） as well as changes of abdominal girth，liver function（ALT，AST，ALB，TBil and A/G） and prothrombin time before and after treatment were compared between groups.Results Difference of therapeutic effects in the two groups was statistically significant（P 　　【Key words】MTMZ，method of soothing liver and strengthening spleen，ascites due to cirrhosis 　　肝硬化是一种由不同病因长期作用于肝脏引起的慢性、进行性、弥漫性肝病的终末阶段[1]。临床主要表现为肝功能衰退和门静脉高压等所引起的一系列症状和体征。在中医学属“膨胀”、“单腹水”、“肝水”等，是中医学的四大顽症之一，预后不良。其