中药红花浸液辅助腹腔镜下手术治疗子宫内膜异位症对于生育指数影响.docVIP

中药红花浸液辅助腹腔镜下手术治疗子宫内膜异位症对于生育指数的影响 　　【摘要】目的：探讨中药红花浸液辅助腹腔镜手术治疗子宫内膜异位症对生育功能的影响。方法：连续选择2013年1月至2014年1月来我院诊断为EMT患者共90例，取得我院伦理委员会通过和患者及家属的知情同意权后，将其随机分为观察组和对照组各45例，观察组行中药红花浸液+腹腔镜手术，对照组行开腹手术，对比两组法人临床疗效差异性。结果：观察组的住院以及疼痛持续时间均显著少于对照组，差异有统计学意义（P0.05）。治疗后两组患者血清CA-125和LIF蛋白表达水平均降低，且观察组降低的更明显，差异均有统计学意义（P0.05）。两组随访约6个月后，观察组患者的总有效率和妊娠率均显著高于对照组，差异均有统计学意义（P0.05）。 结论：中药红花浸液辅助腹腔镜手术治疗子宫内膜异位症疗效显著，优于常规手术疗法。 　　【关键词】红花；腹腔镜；子宫内膜异位症 　　Effect of Safflower extraction assisted laparoscopic operation for endometriosis on fertility indexZHANG Xuan1， LIU Yi2△， LI Bin1， KE Lina1， WANG Yingli1， HUANG Yaxiong1. 1.Department of Obstetrics and Gynecology， Dongfeng General Hospital， Hubei University of Medicine， Shiyan 442008， Hubei， China；2.Department of Urology， Dongfeng General Hospital， Hubei University of Medicine， Shiyan 442008， Hubei， China 　　【Abstract】Objectives： To study effect of Safflower extraction assisted laparoscopic operation for endometriosis on fertility index. Methods： A total of 90 consecutives diagnosed as endometriosis from January 2013 to January 2014 were divided randomly into experiment and control groups， each of 45 cases. The patients in experiment group received Safflower extraction assisted laparoscopic operation， while patients in control group received common laparotomy. Effect of the two groups was compared. Results： The in-hospital and pain persisting time in experiment group was all significantly less than control group （P0.05）. The expression levels of CA125 and LIF protein after treatment in both groups were lower， more significant in experiment group than control group （P0.05）. The total efficacy rate and pregnancy rate in experiment group were significantly less in follow-up （P0.05）. Conclusions： Safflower extraction assisted laparoscopic operation is prior to common laparotomy in treating endometriosis. 　　【Key words】Safflower； Laparoscopy； Endometriosis 　　【中图分类号】R713.4【文献标志码】A 　　子宫内膜异位症（EMT）发病率约1%～7%，在不孕群体中约33%，EMT患者不孕症几率约30%～50%；而且20%～90%的慢性盆腔痛和40%～60%的痛经与此相关