影像导航引导经鼻内镜在鼻颅底肿瘤切除中应用.docVIP

影像导航引导经鼻内镜在鼻颅底肿瘤切除中应用 　　[摘要] 目的 探讨在影像导航的引导下经鼻内镜技术应用于鼻颅底肿瘤的切除中的临床价值。方法 方便选择的研究对象为在2008年10月―2014年10月期间，该院收治的50例鼻颅底肿瘤患者，均行鼻内镜手术治疗，其中20例患者在影像导航的引导下进行手术，将其作为研究组；另外30例患者行单纯的鼻内镜手术，作为对照组，比较两组患者的手术时间、住院时间、术中出血量及术后并发症等指标。结果 在手术时间、住院时间、术中出血量指标上，研究组分别为（168.5±20.3）min、（8.25±3.5）d、（120. 5±11.3）mL，对照组分别为（170.6±20.6）min、（9.5±5.3）d、（123.5±10.6）mL，两组患者差异无统计学意义（P0.05）；在脑脊液鼻漏及眼部肿胀的发生率上，研究组患者的发生率分别为5.0%、10.0%，均明显低于对照组的10.0%、20.0%，经统计学分析后，差异有统计学意义（P0.05）。结论 在影像导航的引导下经鼻内镜进行鼻颅底肿瘤的切除，有着定位精确、术中创伤小的优势，从而可以避免并发症的出现，有着重要的临床参考意义。 　　[关键词] 鼻颅底；肿瘤；鼻内镜；影像导航 　　[中图分类号] R739.6 [文献标识码] A [文章编号] 1674-0742（2016）06（a）-0194-03 　　[Abstract] Objective To observe the clinical value of applying image navigation in guidance of on skull base tumor resection through endoscopic techniques. Methods Convenient selection the subjects were 50 cases of skull base tumor patients selected from October 2008 - October 2014 in our hospital， all of whom were underwent endoscopic sinus surgery， including 20 cases of patients under the guidance of image navigation， as a research group； while another 30 patients underwent endoscopic sinus surgery alone， as a control group. After surgery the operative time， hospital stay， blood loss and postoperative complications and other indicators of the two groups were compared. Results In the operative time， hospital stay， the blood loss index， the study group were（168.5±20.3），（8.25±3.5），（120.5±11.3）， control group were （170.6±20.6），（9.5±5.3），（123.5±10.6）， there was no significant difference of patients from the two groups（P0.05）；in the incidence of cerebrospinal fluid rhinorrhea and eye swelling of patients ， the incidence in the study group patients was respectively 5.0% and10.0%， were significantly lower than the 10.0% and 20.0% in the control group， the difference was significance （P 0.05）. Conclusion Performing endoscopic skull base tumor resection under the guidance of image navigation has the advantage of positioning accuracy and less intraoperative trauma， thereby complications