超声造影在肝脏局灶性病灶诊断及鉴别诊断中价值.docVIP

超声造影在肝脏局灶性病灶诊断及鉴别诊断中价值 　　[摘要] 目的 探讨超声造影在肝脏局灶性病灶中的诊断及鉴别诊断中的价值。 方法 选取我院2014年1月～2016年1月进行常规超声检查的34例患者，共有41个占位性病变。根据病理检查结果将41个病灶分为两组，恶性病变17个为观察组和24个良性病变为对照组，将常规超声和超声造影检查结果与病理结果进行对照，对各项检查的灵敏度、特异度和准确度进行比较，采用时间-强度曲线进一步对肝脏局灶性病灶的良恶性进行鉴别。 结果 对肝脏局灶性病灶诊断的灵敏度、特异度、准确度超声造影分别为87.5%、95.5%、85.4%，常规超声分别为61.1%、84.2%、65.9%，差异有统计学意义（P0.05）。开始增强时间、达峰时间、始消时间、峰值强度定量值良性病灶和恶性病灶记录值比较，差异均有统计学意义（P0.05）。 结论 超声造影明显提高了超声对肝局灶性病灶诊断的灵敏度、特异度和准确度，且超声造影通过分析时间-强度曲线的定量参数变化对鉴别病灶的良恶性具有重要价值。 　　[关键词] 肝脏局灶性病灶；超声造影；常规超声；诊断；鉴?e诊断 　　[中图分类号] R445.1 [文献标识码] A [文章编号] 1674-4721（2016）05（c）-0054-03 　　Contrast-enhanced ultrasound in the diagnosis and differential diagnosis of hepatic focal liver lesion 　　HUANG Yu-hong CHEN Wei-jun LIANG Yan-yan 　　Clinical Laboratory Instrument，People′s Hospital of Yangjiang City in Guangdong Province，Yangjiang 529500，China 　　[Abstract] Objective To explore the contrast-enhanced ultrasound in the diagnosis and differential diagnosis of hepatic focal liver lesion. Methods 34 patients who conducted routine ultrasound examination from January 2014 to January 2016 in our hospital were selected，and a total of 41 space-occupying lesions.41 lesions were divided into two groups according to pathological findings.17 malignant lesions were divided into observation group，and 24 benign lesions were divided into control group.The results of routine ultrasound and contrast-enhanced ultrasound examination were compared with pathological findings.The sensitivity，specificity and accuracy of all examinations were compared.Time-intensity curve was used to further identify the malignant or benign of focal liver lesion. Results The sensitivity，specificity and accuracy of contrast-enhanced ultrasound in diagnosis focal liver lesion were respectively 87.5%，95.5% and 85.4%，which were respectively 61.1%，84.2% and 65.9% in routine ultrasound，and the difference was statistical significance when compared with two groups （P0.05）.All of beginning enhanced time，time to peak，washout time，peak intensity quantitat