阿司匹林与氯吡格雷在冠心病抗血小板治疗中应用分析.docVIP

阿司匹林与氯吡格雷在冠心病抗血小板治疗中应用分析 　　【摘要】 目的：探讨在冠心病治疗中应用阿司匹林与氯吡格雷进行抗血小板治疗的应用效果。方法：选取2014年12月-2016年12月笔者所在医院收治的冠心病患者52例作为研究对象，随机分为A组（阿司匹林）、B组（阿司匹林+氯吡格雷）各26例。观察两组患者治疗总有效率、治疗前后血小板聚集率、血小板反应指数、心血管事件发生情况。结果：B组患者治疗总有效率高于A组，比较差异有统计学意义（P0.05）；治疗后，两组的血小板聚集率及血小板反应指数均低于治疗前，B组血小板聚集率及血小板反应指数均低于A组，比较差异均有统计学意义（P0.05）；B组患者心血管事件发生率低于A组，比较差异有统计学意义（P0.05）。结论：阿司匹林与氯吡格雷能够有效降低血小板聚集率及血小板反应指数，减少心血管事件的发生，提高疗效，有助于患者的治疗与康复。 　　【关键词】 阿司匹林； 氯吡格雷； 冠心病； 抗血小板 　　doi：10.14033/j.cnki.cfmr.2017.32.004 文献标识码 A 文章编号 1674-6805（2017）32-0009-02 　　Application of Aspirin and Clopidogrel in Antiplatelet Therapy of Coronary Heart Disease/QI Junhua.//Chinese and Foreign Medical Research，2017，15（32）：9-10 　　【Abstract】 Objective：To explore the application of Aspirin and Clopidogrel in antiplatelet therapy in the treatment of coronary heart disease（CHD）.Method：From December 2014 to December 2016，52 patients with coronary heart disease in our hospital were selected and randomly divided into group A（Aspirin） and group B（Aspirin+Clopidogrel），26 cases in each group.The total effective rate，the platelet aggregation rate，the platelet response index and the incidence of cardiovascular events were observed before and after treatment.Result：The total effective rate of group B was higher than that of group A，the difference was statistically significant（P0.05）；After treatment，the platelet aggregation rate and platelet response index of the two groups were lower than those before treatment，the platelet aggregation rate and the platelet response index in group B were lower than those in group A，the differences were statistically significant（P0.05）；the incidence of cardiovascular events in group B was lower than that in group A，and the difference was statistically significant（P0.05）.Conclusion：Aspirin and Clopidogrel can effectively reduce platelet aggregation rate and platelet response index，reduce the incidence of cardiovascular events，improve the curative effect，and help patients with treatment and rehabilitation. 　　【Key words】 As