雌孕激素联用对于药物流产后阴道出血疗效及对激素水平影响分析.docVIP

雌孕激素联用对于药物流产后阴道出血疗效及对激素水平影响分析 　　【摘要】目的：探讨雌-孕激素序贯治疗药物流产后阴道出血的临床效果及对患者激素水平的影响分析。方法：采用随机数字表法将本院收治的87例行药物流产者随机分为雌孕激素组44例和对照组43例，两组均常规止血、消炎治疗，雌孕激素组加用雌孕激素治疗，观察两组患者的出血时间、出血量、流产结局及体内激素水平等指标的变化情况差异。结果：雌孕激素组患者的引导出血量少量的比例63.64%显著的高于对照组的32.56%，雌孕激素组的出血量、出血时间显著的低于对照组（P0.05），7d后两组的E2均显著的增高、P显著的降低（P0.05），7d后两组的E2均显著的增高、P显著的降低（P0.05）。结论：雌-孕激素序贯治疗药物流产后阴道出血能显著的缩短出血时间、促进月经复潮、激素水平恢复。 　　【关键词】雌-孕激素；药物流产；阴道出血；临床效果 　　Effect of joint use of estrogen and progesterone on vaginal bleeding after drug abortion and hormone levelsLIN Xuewan1， JIANG Chao2. 1. Department of Obstetrics and Gynecology， Haikou Third People’s Hospital， Haikou 571100， Hainan， China； 2. Department of Obstetrics and Gynecology， The Hospital Affiliated to Hainan MedicalCollege， Haikou 571100， Hainan， China 　　【Abstract】Objectives： To analyze the clinical effect of joint use of estrogen and progesterone on vaginal bleeding after drug abortion and hormone levels in patients. Methods： 87 patients receiving drug abortion were randomly divided into estrogen and progesterone group （44 cases） and control group （43 cases）. Both groups were treated with conventional hemostasis and anti-inflammatory therapy. The estrogen and progesterone group was additionally treated with hormone therapy. The difference in bleeding time， bleeding quantity change， abortion outcome and hormone the level of the two groups was observed. Results： The proportion of patients with little bleeding amount in estrogen and progesterone group was 63.64%， higher than that of the control group （32.56%）； the amount of bleeding and bleeding time of estradiol and progesterone group was significantly lower than that of the control group （P0.05）， and 7d later the E2 of the two groups significantly increased while P levels decreased significantly （P0.05）. Conclusions： Estrogen and progestogen sequential therapy in the treatment of vaginal bleeding after drug abortion can significantly shorten the bleeding time， menstruation， hormone levels and promote the recovery.