高频超声对健康体检人群中甲状腺微小癌筛查作用研究.docVIP

高频超声对健康体检人群中甲状腺微小癌筛查作用研究 　　【摘要】 目的 探讨高频超声对甲状腺微小癌（TMC）的筛查诊断价值。方法 选取108例经过手术或穿刺病理证实的甲状腺微小癌患者（甲状腺微小癌组）， 以同期最常见、最易混淆的108例结节性甲状腺肿小结节患者（甲状腺肿小结节组）作为对照， 对两组进行高频二维超声筛查， 对比总结两组的筛查结果。结果 甲状腺微小癌组在形态不规则、周围无回声、甲状腺边缘中断、内部低回声、边界不清晰、微钙化灶、无声晕、无囊性变、纵横比（A/T）1方面的血流分布比例高于甲状腺肿小结?组， 差异有统计学意义（P0.05）。甲状腺微小癌组患者的血流收缩期峰值流速（PSV）为（45.49±8.29）cm/s， 　　阻力指数（RI）为（0.69±0.16）， 明显高于甲状腺肿小结节组的（35.44±8.14）cm/s、（0.52±0.14）， 差异具有统计学意义（P1及微钙化， 血流丰富程度， 瘤体周围及颈部多发淋巴结有助于甲状腺微小癌的诊断， 高频超声对甲状腺微小癌具有重要的筛查作用， 综合分析二维及彩色多普勒超声图像特点， 可提高甲状腺微小癌检出率。 　　【关键词】 高频超声；健康体检人群；甲状腺微小癌 　　DOI：10.14163/j.cnki.11-5547/r.2017.08.007 　　【Abstract】 Objective To explore the screening and diagnostic value of high-frequency ultrasound for thyroid micro-carcinoma （TMC）. Methods There were 108 thyroid micro-carcinoma patients confirmed by operation or puncture pathology （thyroid micro-carcinoma group）， and concurrent 108 most common and most easily confused nodular goiter nodules patients （goiter nodules group） as a comparison. High frequency two-dimensional ultrasound screening was made in two groups， and their screening results were compared and summarized. Results The thyroid micro-carcinoma group had better aspects of irregular shapes， anechoic around， thyroid edge disruption， low internal echo， boundary fuzziness， microcalcifications， no acoustic halo， no cystic change， anteroposterior/transverse diameter ratio （A/T）1 than goiter nodules group， and the difference had statistical significance （P0.05）. The thyroid micro-carcinoma group had peak systolic velocity （PSV） as （45.49±8.29） cm/s， resistance index （RI） as （0.69±0.16）， which were obviously higher than （35.44±8.14） cm/s and （0.52±0.14） in goiter nodules group， and their difference had statistical significance （P 1 and microcalcification， blood flow richness， and frequent ymph nodes around tumors and neck are helpful for diagnosis of thyroid micro-carcinoma， and high-frequency ultrasound has important screening effect for thyroid micro-carcinoma. Comprehensive analysis of two-dimensio