咪唑斯汀和雷尼替丁联用治疗慢性特发性荨麻疹疗效和不良反应分析.docVIP

咪唑斯汀和雷尼替丁联用治疗慢性特发性荨麻疹疗效和不良反应分析 　　DOI：10.16662/j.cnki.1674-0742.2016.32.014 　　[摘要] 目的 研究分析咪唑斯汀?c雷尼替丁联用治疗慢性特发性荨麻疹疗效及安全性。 方法 2014年5月―2016年5月期间，整群选择该院接收的慢性特发性荨麻疹患者72例作为研究对象，将72例患者随机分为两组，观察组36例和对照组36例，对照组患者应用咪唑斯汀进行治疗，观察组患者应用雷尼替丁联合咪唑斯汀进行治疗，对比观察组与对照组的治疗效果。结果 观察组患者治疗前症状积分（2.76±0.65）分与对照组（2.70±0.52）分差异无统计学意义（P0.05）；观察组患者治疗后症状积分（0.73±0.62）分优于对照组（1.59±0.68）分，差异有统计学意义（P0.05）。 结论 咪唑斯汀与雷尼替丁联用治疗慢性特发性荨麻疹的效果较好，安全性高，值得推广应用。 　　[关键词] 咪唑斯汀；雷尼替丁；慢性特发性荨麻疹；疗效 　　[中图分类号] R758 [文献标识码] A [文章编号] 1674-0742（2016）11（b）-0014-03 　　Ranitidine Imidazole Sting and Adjunctive Therapy for Chronic Idiopathic Urticaria Curative Effect and Adverse Reactions to Observe 　　FAN Su-jing 　　Department of Dermatology， Hospital of Guanyun County， Lianyungang City， Jiangsu Province， Lianyungang， Jiangsu Province， 222200 China 　　[Abstract] Objective To study the analysis of ranitidine imidazole westin and adjunctive therapy for chronic idiopathic urticaria efficacy and safety. Methods Group selection May 2014 to May 2016， choose 72 patients with chronic idiopathic urticaria in our hospital to receive as the object of study， 72 patients were randomly divided into two groups， 36 cases observation group and control group 36 cases， control group patients using imidazole sting treatment， joint ranitidine group patients imidazole sting treatment， compared the curative effect of observation group and control group. Results Observation group patients before symptoms （2.76 ± 0.65） points and the control group （2.70±0.52） and no significant difference， there is no statistical significance（P 0.05）； Observation group after treatment in patients with symptoms （0.73 ± 0.62） points is better than that of control group （1.59±0.68）， significant difference was statistically significant （P 0.05）. Conclusion Ranitidine imidazole westin and adjunctive therapy for chronic idiopathic urticaria effect is good， high safety， is worthy of popularization and application. 　　[Key words] Imidazole sting； Ranitidine； Chronic idiopathic u