基于大鼠脑梗塞模型的脑电与心电变化的关联性研究-生物医学工程专业论文.docxVIP

作者签g：越飞f蛑三月强长春理工大学学位论文版权使用授权书 作者签g：越飞f蛑三月强 长春理工大学学位论文版权使用授权书 一一一一一一 纛器 作者豁i监豇1业年如瑚 导师签名 礁二三年．L月兰咱 摘要在临床上脑梗塞患者同时合并有心电图改变的情况是非常常见的。急性脑血管疾 摘要 在临床上脑梗塞患者同时合并有心电图改变的情况是非常常见的。急性脑血管疾 病弄凸急性心血管疾病的关系．是当今临床研究的热点之一．相蓑研究表明脑梗塞急性 期T波异常和sT段异常的发生率显著增高。随着脑血管疾病发病率的增加，由其所 引发的心脏活动异常也逐渐引起广大临床工作者的重视。 本课题以wistar大鼠为实验对象，采用光化学原理方法建立大鼠脑梗塞模型．研 究大鼠脑梗塞时期的心电与赫电信号的变化情况。利甩多生理参数记录仪同步采集大 鼠脑梗塞前后的EEG与ECG信号，通过对脑电的非线性参数的计算来判定丈鼠脑梗 塞的程度，并利用小波变换理论以MATLAB为平台分别实现脑电信号和心电信号的特 征检测和处理。最后应用数据挖掘技术中的关联规则算法实现脑电与心电信号特征变 化的关联性研究。挖掘出的关联规则揭示了脑电与心电信号特征变化之间潜在的、有 价值的关系，为脑梗塞和心血管疾病的诊断和预防提供重要的参考依据。 关键词：关联分析EEG ECG大鼠脑梗塞模型 Abstractit Abstract it is very eolItrfloll that patients with cerebra】infarction are often along with the clinical ECG changing The clinicaI research of acute cerebra】vascular diseases and aeute cardiovascular diseases js ode of the hots today,related studies have shown th乱the probability of T-wave abnormalities and ST segment abnormalities was significantly 】ncreased whne acute cerebr抽1nfarction OCCURS With the incidence of cerebrovascular disease increasing，the abnormal changes of hearl’activities have gradually aroused the attention ofmedleal workers The topic USeS wistar rats as experimental subjects．makes the model of cerebral infarction in rats based on photochemistry principle，and studys the changes of the ECG signal and EEG signal based on the roodel of cerebral lnfarction rats We gathered synchronousEEG andECG signals before and aftercerebralinfarctionin rats usingMultiple Physiological parameters R∞order,determined the extent of cerebraI infarction ln rats by calculatingEEG Non．1inearparamet自：s andmadeⅥseofwavelettransform伽eorytoprocess and getEEG andECGfeatures ontheplatform ofMATLAB Fitlally,found outthe relevance between EEG and ECG features applying associmion rules algorithm of data m岫“g The associatiOn roles mined out revealed the potential and valuable relationship ofcharacteristic changes between EEG signal and ECG signal It can provide an impormm reference for cerebral mfarcdon end cardiova