伤必止对家兔的长期毒性实验研究.docxVIP

伤必止对家兔的长期毒性实验研究 【摘要】 目的考察伤必止对家兔 皮肤用药的长期毒性。方法 16只家兔随机 分成4组，连续用药4周。每天观察记录其 一般情况，药后做血液学及血液生化指标检 查，计算脏器系数并进行组织病理学检查。 结果伤必止各剂量组未见毒性反应， 与空白 对照组比较均无显着性差异。结论伤必止长 期外用是安全的。 【关键词】 伤必止； 长期毒性； 家兔 Abstract : ObjectiveTo observe the long-term toxicity of Shangbizhi on local skin of rabbits. Methods16 rabbits were randomly divided into 4 groups treated with drug for a consecutive 4 weeks. The general conditions of rabbits were observed every day. The blood analysis and blood biochemical examination were performed after drug administration. The organ coefficient was calculated and pathological change was toxi