国产苯磺酸氨氯地平片与吲达帕胺治疗原发性高血压高龄患者的疗效.docVIP

421001421001）80岁）患者的临床疗效苯磺酸氨氯地平片与呀达帕胺片治疗原发性高血压高龄患者的疗效比较 421001 421001）80岁）患者的临床疗效 （1、湖南环境生物职业技术学院， 湖南 衡阳 2、南华大学附属第一医院， 湖南衡阳 ［摘要］ 目的:观察苯磺酸氨氯地平片治疗原发性高血压高龄（ 和安全性。方法：105例高龄高血压患者随机分为2组,1组（n = 53）给予苯磺酸氨氯地 平5 mg?d -1 ; II组（/7二52）给予II引达帕胺2. 5 mg ? d ■1，观察8周。结果：治疗后两 组收缩压和舒张压均有明显降低,与治疗前比较有统计学意义（戶〈0. 05） , I纽的降床幅度 略优于11纟II,但两纽间疗效差异无统计学意义（P 0. 05），苯磺酸氨氯地平片的不良反应少 于H引达帕胺片。结论:苯磺酸氨氯地平片治疗原发性高血压高龄患者安全有效，可作为原发性 高血压高龄患者的降压-?线用夯0 ［关键词］高龄人；高血压：苯磺酸氨氯地平片；呵达帕胺片 Comparision of Therapy on Treating Primary Hypertension Senile Patients between Amlodipine Besylate Tablets and Indapamide Tablets 2 Liu Jian Kuang Hongying^ (1. Hunan Environment-Biological Polytechnic,Hengyang, Hunan, 421001 2. The First Hospitdl Affiliated to Nanhua University, Ilengyang, Hunan, 421001) Abstract: Objective：0bserving clinical therapy and security of treating primary hypertension hypcrtension scnilc(80 years) patients on amlodipine besylate tablets? Methods: 105 senile primary hypertension patients were divided randomly into two groups?The patients in group I (口二53) took amlodipine besylate tablet(5mg/d) by mouth;the p“tients in group II (n=52) took indapamide tablet(2?5mg/d) by mouth. They were observed in eight weeks. Results: Both systolic blood pressure and diastolie blood pressure decreased obviously after treatment in each group. There was stdtistical significance compared wi th two groups before treatment(P〈0. 05) ? The affect of decreasing blood pressure i n group I was superior to the affec t in group II, but t here was no st at i st ical significance(P0.05). The adverse drug reactions in amlodipine besylate tablets were less than adverse drug reactions in indapaniide tablets. Conclusion: It is safe and effective that amlodipine besylate tablets treat senile primary hypertension patients. Amlodipine besylate tablets can be used to decrease blood pressure as a chief drug. Key words：Senile Patients;Primary Hypertension; Amlodipine Besylate Tablets; Indapamide Tablets 高血压是冃前常见的心血管疾病z—,是冠心病的主耍危险因素，不仅发生 率高，而且还会