活血散结中药外用治疗老年乳腺增生病模型大鼠的疗效研究.docVIP

活血散结中药外用治疗老年乳腺增生病模型大鼠的疗效研究 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：活血散结中药外用治疗老年乳腺增生病模型大鼠的疗效研究 1 1 材料与方法 3 2 结 果 6 3 讨 论 8 文2：活血散结中药外用治疗老年痰瘀互结型乳腺增生病的疗效临床医学 10 1 资料与方法 11 2 结 果 12 3 讨 论 13 参考文摘引言： 15 原创性声明（模板） 17 文章致谢（模板） 17 正文 活血散结中药外用治疗老年乳腺增生病模型大鼠的疗效研究 文1：活血散结中药外用治疗老年乳腺增生病模型大鼠的疗效研究 【Abstract】 Objective To investigate the mechanism of Huoxuesanjie external use for hyperplasia of mammary gland. Methods 60 aged rats were randomly divided into control, model, Sanjierubi emplastrum, tamoxifen paste, Huoxuesanjie traditional Chinese estraderm elements extracting solution small, middle and large dose groups. Hyperplasia mammary gland model rats were made by the union of estrogen and progestational hormone. At the same time of making model, the rats were given different durg. The body weight, hemorheology, breast hemodynamic, height and diameter of the left second ripple and serum hormone level were detected before and after treatment. Results Compared with control group, the body weight increasing degree decreased in model and each treatment groups on second week(P＜) and regain the normal level on the third week. The mammary gland circulation perfusion in control group was higher than that of model and each treatment groups (P＜). After drug interference, the mammary gland circulation perfusion in each treatment group was higher than that of model group (P＜), and the mammary gland circulation perfusion in Huoxuesanjie middle and large dose group was higher than that of sanjierubi group(P＜). Huoxuesanjie could improve the model rat′s blood high viscosity and highcoagulate state. The change of ripple height in each treatment group could be inhibited (P＜) and the effect of large and middle dose of Huoxuesanjie were better than that of small dose of Huoxuesanjie and sanjierubi (P＜). Except small dose of Huoxuesanjie, the other drug could inhibite the change of ripple diameter (P＜), and tamoxifen was better than other drugs and there was obviou