症状性椎基底动脉狭窄患者支架置入术后再狭窄有关因素浅析.docVIP

症状性椎基底动脉狭窄患者支架置入术后再狭窄有关因素浅析 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：症状性椎基底动脉狭窄患者支架置入术后再狭窄有关因素浅析 1 1 资料与方法 3 2 结果 4 3 讨论 5 文2：经皮血管内支架成形术治疗症状性椎基底动脉狭窄 7 1 对象和方法 7 2 结果 9 3 讨论 9 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 11 正文 症状性椎基底动脉狭窄患者支架置入术后再狭窄有关因素浅析 文1：症状性椎基底动脉狭窄患者支架置入术后再狭窄有关因素浅析 【Abstract】 Objective To investigate the clinical correlated facto of restenosis in patients with symptomatic vertebrobasilar artery(VBA) stenosis after stenting. Methods The clinical data of 36 patients with symptomatic VBA stenosis after stenting were analyzed. The restenosis rate after stenting was followedup with tracranial Doppler(TCD)，color Doppler imaging(CDI) and digital subtraction angiography(DSA). Eleven facto including cerebral infarction risk facto，target lesion length and target lesion position etc were chosed， and then the data and their correlatio with restenosis were analyzed. The significant differences for the restenosis rate with and without related risk facto were examined by ChiSquare test. Results There were 40 stenosis in 36 patients， and 40 stents were placed in these mean followup time was ± patients were followedup with TCD，CDI，and six with DSA，eight patients(8/36，%) had restenosis more than 50%.The percentage of diabetic mellitus history in restenosis group was higher than nonrestenosis group(%，% separately，P＜);The percentage of target lesio in vertebral artery ostium in restenosis group was higher than nonrestenosis group(%，% separately，P＜);The percentage of target lesio length≥10mm in restenosis group was higher than nonrestenosis group(%，% separately，P＜).Conclusion Diabetic mellitus history， target lesio in vertebral artery ostium and target lesion length were probable predicto of VBA poststenting restenosis。 【Key words】 Vertebrobasilar artery; Stent; Risk facto; Restenosis 症状性椎基底动脉狭窄引起的脑卒中临床预后较差，Rasmussen等［1］报告在5年内有25%～30%的椎基底动脉TIA病人发生致死性事件，病死率及致残率高，因此需要积极的治疗，由于药物治疗效果甚微，外科手术在技术上存在较大困难及潜在危险，因此，许多学者选择血管内治疗［2］，通过重建病变血