会阴部Paget病广泛切除术后并发急性肾损伤1例并文献复习.pdfVIP

临床论著 OriginalResearch 会阴部Paget病广泛切除术后并发急性肾损伤1例 并文献复习 郭燕妮 谭 谦 南京大学医学院附属鼓楼医院整形烧伤科 (江苏 南京 210093) 【摘要 】目的 探讨乳房9bPaget病及急性肾损伤的的诊断、治疗及预后特点。方法 结合文献分析一例会阴 部Paget病术后并发急性肾损伤患者的临床资料。结果 乳房外Paget病是一种较少见的皮肤恶性肿瘤，临床 表现缺乏特异性，诊断主要依靠病理组织学及免疫组化；老年人肾脏功能减退，在围手术期需加强液体管 理，预防’肾脏并发症。结论 乳房PbPaget病首选手术治疗，术后复发与手术切除范围有关；急性’肾损伤治疗 关键在于原发病及致病因素的治疗，同时早期给予肾脏替代与有效的支持治疗。 【关键词】乳房~Paget病；皮肤恶性肿瘤；急性肾损伤；并发症 【中图分类号】R739．5；R692．5 【文献标识码 】A O2 DOI：10．3969／j．iSsn．1009—3257．2O14．O6． Extramammary PagetDisease ofPerineum with a Postoperative Complication of AcuteKidneyInjury：aCaseReportandLiteratureReview GUO YaD-nl，TAN Qian． A【bs删 D酗 Toreview theexperiencein thediagnosisandtreatmentofextramammaryPagetdisease andacutekidneyinju andanalyzetheclinicalcharacteristics．Methoa~wepresentonecaes ofextramammary Pagetdiesaes who was performed a wide localexci~on． Buthe had a postoperative complication of acute kidney injury．Hismedicalrecordswere analyzed retrospectively and theliteraturewasreviewed．Resu／W ExtramammaryPagetdiesaes iSan uncommon malignantskin tumor．Itiseasy tomisdiagnoes forlack specific clinicalmanifestanon．Itsdiagnosisshould beconfirmed with pathologicalexamination and immunohistochemical staining．In Ordert0preventtheesriouscomplicationsofkidney．strictfluid managementiSvery importantfor theelderlyduringperioperativeperiod．Cal盘a 岛 Surgicaltreatmentisthefirstchoicetotreatextramammary Pagetdiesaes．The treatmentof acute renalfailure hingeson identification and treatmentof the underlying caues ．The early renalreplacementtherapy and efficient supporttreatmentare very important measuresto criticalpatients． 何 word~lExtramammary PagetDiseaes；MalignantSkinTumorlAcuteKidneyInjury；Complication 作者简介：郭燕妮，女，整形烧伤外科，南京大学医学院在读硕士，研究方向：组织损伤修复的基础与临床研究 通讯作者：谭 谦 5 JOURNALOF RARE AND UNCOMMON DISEASES，DEC．2014，Vo1．