BrainNetVis An Open-Access Tool to Effectively Quantify and Visualize Brain Networks英文文献资料.docVIP
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BrainNetVis An Open-Access Tool to Effectively Quantify and Visualize Brain Networks英文文献资料
HindawiPublishingCorporation
ComputationalIntelligenceandNeuroscience
Volume2011,ArticleID747290,12pages
doi:10.1155/2011/747290
ResearchArticle
BrainNetVis:AnOpen-AccessToolto
EffectivelyQuantifyandVisualizeBrainNetworks
EleniG.Christodoulou, VangelisSakkalis, VassilisTsiaras,
1 1 2andIoannisG.Tollis 1,2
1
InstituteofComputerScience(ICS),FoundationforResearchandTechnology—Hellas(FORTH),N.Plastira100,
GR-70013Heraklion,Greece
2
DepartmentofComputerScience,UniversityofCrete,GR-71409Heraklion,Greece
CorrespondenceshouldbeaddressedtoEleniG.Christodoulou,echristo@ics.forth.gr
Received17September2010;Revised25November2010;Accepted31December2010
AcademicEditor:SylvainBaillet
Copyright?2011EleniG.Christodoulouetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution
License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly
cited.
ThispaperpresentsBrainNetVis,atoolwhichservesbrainnetworkmodellingandvisualization,byprovidingbothquantitative
and qualitative network measures of brain interconnectivity. It emphasizes the needs that led to the creation of this tool by
presentingsimilarworksinthe?eldandby describinghowourtoolcontributes totheexistingscenery.Italsodescribes the
methodsusedforthecalculationofthegraphmetrics(globalnetworkmetricsandvertexmetrics),whichcarrythebrainnetwork
information.Tomakethemethodsclearandunderstandable,weuseanexemplardatasetthroughoutthepaper,onwhichthe
calculationsandthevisualizationsareperformed.Thisdatasetconsistsofanalcoholicandacontrolgroupofsubjects.
1.Introduction
thresholdvalue.Inpractice,abroadrangeofthresholdvalues
is used to characterize the network. However, the authors
proposetwoalternativeapproachesinselectingathreshold
valuebasedeitherongroupstatisticsbetweenspeci?cgraph-
theoreticmeasuresofthepopulationsunderanalysis[6]or
utilizing a signal-based technique of selecting the optimal
visualizationthresholdusingsurrogate(
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