BrainNetVis An Open-Access Tool to Effectively Quantify and Visualize Brain Networks英文文献资料.docVIP

BrainNetVis An Open-Access Tool to Effectively Quantify and Visualize Brain Networks英文文献资料.doc

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BrainNetVis An Open-Access Tool to Effectively Quantify and Visualize Brain Networks英文文献资料

HindawiPublishingCorporation ComputationalIntelligenceandNeuroscience Volume2011,ArticleID747290,12pages doi:10.1155/2011/747290 ResearchArticle BrainNetVis:AnOpen-AccessToolto EffectivelyQuantifyandVisualizeBrainNetworks EleniG.Christodoulou, VangelisSakkalis, VassilisTsiaras, 1 1 2andIoannisG.Tollis 1,2 1 InstituteofComputerScience(ICS),FoundationforResearchandTechnology—Hellas(FORTH),N.Plastira100, GR-70013Heraklion,Greece 2 DepartmentofComputerScience,UniversityofCrete,GR-71409Heraklion,Greece CorrespondenceshouldbeaddressedtoEleniG.Christodoulou,echristo@ics.forth.gr Received17September2010;Revised25November2010;Accepted31December2010 AcademicEditor:SylvainBaillet Copyright?2011EleniG.Christodoulouetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. ThispaperpresentsBrainNetVis,atoolwhichservesbrainnetworkmodellingandvisualization,byprovidingbothquantitative and qualitative network measures of brain interconnectivity. It emphasizes the needs that led to the creation of this tool by presentingsimilarworksinthe?eldandby describinghowourtoolcontributes totheexistingscenery.Italsodescribes the methodsusedforthecalculationofthegraphmetrics(globalnetworkmetricsandvertexmetrics),whichcarrythebrainnetwork information.Tomakethemethodsclearandunderstandable,weuseanexemplardatasetthroughoutthepaper,onwhichthe calculationsandthevisualizationsareperformed.Thisdatasetconsistsofanalcoholicandacontrolgroupofsubjects. 1.Introduction thresholdvalue.Inpractice,abroadrangeofthresholdvalues is used to characterize the network. However, the authors proposetwoalternativeapproachesinselectingathreshold valuebasedeitherongroupstatisticsbetweenspeci?cgraph- theoreticmeasuresofthepopulationsunderanalysis[6]or utilizing a signal-based technique of selecting the optimal visualizationthresholdusingsurrogate(

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