Brainstorm A User-Friendly Application for MEGEEG Analysis英文文献资料.docVIP

HindawiPublishingCorporation ComputationalIntelligenceandNeuroscience Volume2011,ArticleID879716,13pages doi:10.1155/2011/879716 ResearchArticle Brainstorm:AUser-FriendlyApplicationforMEG/EEGAnalysis Franc?oisTadel, SylvainBaillet, JohnC.Mosher, DimitriosPantazis, 1 2 3 4 andRichardM.Leahy 1 1 2 3 4 SignalImageProcessingInstitute,UniversityofSouthernCalifornia,LosAngeles,CA90089,USA MEGProgram,DepartmentsofNeurologyBiophysics,FroedtertMedicalCollegeofWisconsin,Milwaukee,WI53226,USA EpilepsyCenter,ClevelandClinicNeurologicalInstitute,Cleveland,OH44195,USA MEGLab,McGovernInstituteforBrainResearch,MassachusettsInstituteofTechnology,Cambridge,MA02139,USA CorrespondenceshouldbeaddressedtoFranc?oisTadel,tadel@ Received4October2010;Accepted28January2011 AcademicEditor:RobertOostenveld Copyright?2011Franc?oisTadeletal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Brainstormisacollaborativeopen-sourceapplicationdedicatedtomagnetoencephalography(MEG)andelectroencephalography (EEG)datavisualizationandprocessing,withanemphasisoncorticalsourceestimationtechniquesandtheirintegrationwith anatomicalmagneticresonanceimaging(MRI)data.TheprimaryobjectiveofthesoftwareistoconnectMEG/EEGneuroscience investigatorswithboththebest-establishedandcutting-edgemethodsthroughasimpleandintuitivegraphicaluserinterface (GUI). 1.Introduction dependentontheshapeandconductivityofheadtissuesand canbeperformedusinganumberofmethods,rangingfrom simple spherical head models [1] to overlapping spheres [2] and boundary or ?nite element methods [3]. Inverse sourcemodeling,whichresolvesthecorticalsourcesthatgave risetoMEG/EEGrecordings,hasbeenapproachedthrough a multitude of methods, ranging from dipole ?tting [4] todistributedsourceimagingusingBayesianinference[5– 7]. This diversity of models and methods re?ects the