肺腺样囊性癌4例病例报告.docVIP

肺腺样囊性癌4例病例报告 贺玺兰 陈建华 中南大学湘雅医学院 中南大学湘雅医学院附属肿瘤医院胸部内一科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 背景与目的 肺腺样囊性癌是肺癌中的少见类型, 通常对其诊断及治疗认识不足。为了提高对肺腺样囊性癌的认识, 本文对该病例进行了收集和分析。方法 回顾分析我院2012年1月-2016年12月收治的4例肺腺样囊性癌, 对其病理免疫组化、表皮生长因子受体 (epidermal growth factor receptor, EGFR) 及间变性淋巴瘤激酶 (anaplastic lymphoma kinase, ALK) 突变分析、诊断和治疗特点进行总结。结果 肺腺样囊性癌是一种主要发生在气道、EGFR及ALK突变少见、转移较晚、手术治疗效果好的一种疾病。结论 肺腺样囊性癌诊断主要依赖于病理学, 早期以手术治疗为主, 晚期可行放化疗, 但靶向治疗机会不多, 其预后较小细胞肺癌及非小细胞肺癌好。 关键词： 肺腺样囊性癌; 肺肿瘤; 诊断; 治疗; 作者简介：陈建华, E-mail:cjh_1000@163.com 收稿日期：2017-08-26 Four Cases Report on Primary Lung Adenoid Cystic Carcinoma Xilan HE Jianhua CHEN Xiangya School of Medicine Central South University; Department of Thoracic Neoplasms, Hunan Cancer Hospital, the Affliated Cancer Hospital of Xiangya School of Medicine Central South University; Abstract： Background and objective Lung adenoid cystic carcinoma is a kind of rare lung cancer. Diagnosis and treatment is not enough understandable for them. We collected and analyzed 4 cases of lung adenoid cystic carcinoma for broadening the sight of this disease. Methods Retrospectively analysed the 4 cases we collected from Hunan Cancer Hospital Between January 2012 and December 2016. We depicted the pathology, immunohistochemical, epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) arrangement in these cases. And the methods of the diagnosis and treatment were analyzed. Results Lung adenoid cystic carcinoma is usually located in the airway, EGFR mutation and ALK arrangement is rare in this disease. Generally the metastasis of the lung cancer occurred in the advanced stage. The prognosis is good if the mass could be resected completely. Conclusion Diagnosis of the lung adenoid cystic carcinoma depends on pathological experiments, surgery is the main treatment in the early stage, radiotherapy and chemotherapy is an advisable therapy in the advanced stage. And the prognosis of this kind of lung cancer