右美托咪定麻醉对高血压患者苏醒期躁动和血流动力学影响.docVIP

右美托咪定麻醉对高血压患者苏醒期躁动和血流动力学影响 　　[摘要]目的 探索右美托咪定麻醉对高血压患者苏醒期躁动和血流动力学的影响。方法 选择我院2014年7月～2016年7月收治的86例有高血压病史需要进行全麻手术患者的临床资料作为观察对象，根据随机数字表法将其分成试验组和对比组，每组各43例。在手术结束前60 min，给对比组患者静脉微泵注射20 ml生理盐水，给试验组患者静脉微泵注射0.5 μg/kg右美托咪定，比较两组患者全麻睡醒期躁动程度、疼痛程度及T0～T4各时段的血流动力学。结果 试验组患者的苏醒期躁动率（13.95%）明显低于对比组（48.84%），差异有统计学意义（P0.05）；试验组患者术后1 h VAS评分明显低于对比组，差异有统计学意义（P0.05）；试验组患者拔管期各时点的平均动脉压（MAP）、心率（HR）明显低于对比组，差异有统计学意义（P0.05）。结论 右美托咪定对高血压患者麻醉苏醒期的躁动程度的降低有较大的作用，使患者的血流动力学保持稳定，减少患者术后的疼痛程度，提高了患者的苏醒质量。 　　[关键词]高血压；右美托咪定；麻醉苏醒期躁动；血流动力学 　　[中图分类号] R614 [文献标识码] A [文章编号] 1674-4721（2017）05（c）-0056-03 　　[Abstract]Objective To explore the effect of dexmedetomidine on agitation and hemodynamics in hypertensive patients during recovery period.Methods From July 2014 to July 2016，clinical data from 86 hypertensive patients undergone surgeries via general anesthesia were selected as observation objects.According to a random number table，they were evenly divided into experimental group and control group.Sixty minutes before the end of the operation，20 ml saline by intravenous micro-pump injection was used for patients in the control group.In the experimental group，0.5 μg/kg dextromethorphan via intravenous micro-pump injection was applied.Theagitation，pain degree，and hemodynamics at T0 to T4 during recovery period in the two groups were compared.Results In the experimental group，the agitation rate during recovery period was 13.95%，much lower than that in the control group accounting for 48.84% with a statistical difference （P0.05）.The score of VAS one-hour after surgery in the experimental group was greatly lower than that in the control group with a statistical difference （P0.05）.The mean arterial pressure （MAP） and heart rate （HR） at different time points in the experimental group were lower than those in the control group with statistical differences（P0.05）.Conclusion Deemethomidine has a great effect on the reduction of restlessness during anesthesia recovery in hypertensive patients.It maintains the stability of