慢性心力衰竭患者急性加重时血压水平控制对近期疗效影响分析.docVIP

慢性心力衰竭患者急性加重时血压水平控制对近期疗效影响分析 　　[摘要] 目的 探讨慢性心力衰竭患者急性加重时血压水平控制对近期疗效的影响。 方法 随机选取2011年5月―2014年5月在该院治疗的慢性心力衰竭急性加重期患者90例，随机将患者按收缩压水平分为实验组（收缩压80～89 mmHg）、对照组（收缩压90～140 mmHg），给予强心利尿、血管扩张药物等治疗。观察及比较两组患者治疗前后的呼吸频率、心率和血氧饱和度等情况，及近期疗效。 结果 实验组患者的总有效率为86.7%，明显高于对照组的66.7%（P0.05）。两组患者治疗后呼吸频率、心率和血氧饱和度均有不同程度改善，但实验组治疗后临床指标改善更为显著（P0.05）。 结论 慢性心力衰竭患者急性加重时血压水平在一定范围内控制越低，临床症状改善越快，近期临床疗效越好。 　　[关键词] 慢性心力衰竭；急性加重；血压；近期疗效 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2015）08（b）-0058-03 　　[Abstract] Objective To investigate the influence of blood-pressure control for patients with chronic heart failure undergoing acute exacerbation on short-term outcome. Methods 90 patients with chronic heart failure undergoing acute exacerbation who were admitted to our hospital during May 2011 and May 2014 were randomly into experimental group （SBP 80～89mmHg） and control group（SBP 90～140 mmHg） according to systolic blood pressure （SBP）. Cardiotonic and diuretic drugs and vasodilatory drugs were used for their treatment. Respiratory frequency， heart rate， and blood oxygen saturation before and after treatment， and short-term outcomes were observed and compared between the two groups. Results The total effective rate of patients in the experimental group was 86.7%， significantly higher than that in the control group of 66.7%（P0.05）. The respiratory frequency， heart rate and blood oxygen saturation in two groups after treatment were both improved， but those in the experimental group after treatment was improved more significantly（P0.05）. Conclusion Lower blood-pressure in a specific range in patients with chronic heart failure undergoing acute exacerbation can lead to better improvement of clinical symptoms and better short-term outcome. 　　[Key words] Chronic heart failure； Acute exacerbation； Blood pressure； Short-term curative effect 　　慢性心力衰竭（chronic heart failure，CHF））是一种常见、多发的临床心血管疾病，其严重影响患者健康，更有甚者，如发生慢性心力衰竭急性加重时，其预后较差，可危及患者生命，致死率较高[1-2]。该研究探讨了慢性心力衰竭患者急性加重时血压水平控制对近期疗效的影响，现分析2011年5月―2014年5月间在该院治疗的慢性心力衰竭急性加重期患者