早期乳腺癌保乳手术及改良根治术临床疗效对比分析.docVIP

早期乳腺癌保乳手术及改良根治术临床疗效对比分析 　　【摘要】 目的 综合分析早期乳腺癌保乳手术及改良根治术的临床疗效。方法 96例早期乳腺癌患者， 按照术式的不同分为实验组与对照组， 每组48例。实验组患者行保乳术治疗， 对照组患者行改良根治术治疗。对两组患者的临床指标及并发症发生情况进行对比。结果 实验组患者的术中出血量（16.5±2.2）ml、手术时间（114.3±21.2）min、引流量（287.6±37.7）ml、住院时间（9.7±3.2）d均明显优于对照组的（48.1±2.0）ml、（156.2±22.7）min、（566.9±46.8）ml、（13.5±2.8）d， 差异具有统计学意义（P0.05）。实验组患者的并发症发生率2.1%明显低于对照组的14.6%， 差异具有统计学意义（P0.05）。结论 早期乳腺癌患者应用保乳手术的临床疗效显著， 不仅各项手术指标优于改良根治术， 且并发症的发生风险也低于改良根治术， 值得临床推广及应用。 　　【关键词】 改良根治术；乳腺癌保乳手术；生活质量评分；临床效果 　　DOI：10.14163/j.cnki.11-5547/r.2018.09.006 　　【Abstract】 Objective To comprehensively analyze the clinical efficacy of breast conserving surgery and modified radical mastectomy for early breast cancer. Methods A total of 96 early breast cancer patients were divided by different types of operation into experimental group and control group， with 48 cases in each group. The experimental group received breast conserving surgery， and the control group received modified radical mastectomy. Comparison were made on clinical indicators and occurrence of complications between the two groups. Results The experimental group had obviously better intraoperative bleeding volume as （16.5±2.2） ml， operation time as （114.3±21.2） min， volume of drainage as （287.6±37.7） ml and hospitalization time as （9.7±3.2） d than （48.1±2.0） ml， （156.2±22.7） min， （566.9±46.8） ml and （13.5±2.8） d in the control group， and their difference was statistically significant （P0.05）. The experimental group had obviously lower incidence of complications as 2.1% than 14.6% in the control group， and the difference was statistically significant （P0.05）. Conclusion Application of breast conserving surgery shows remarkable clinical efficacy. Not only the operation indexes are superior to modified radical mastectomy， but also the risk of complications is lower than that of radical mastectomy. It is worthy of clinical promotion and application. 　　【Key words】 Modified radical mastectomy； Breast conserving surgery； Quality of life score； Clinical effect