疏血通注射液联合长春西汀治疗急性脑梗死临床价值.docVIP

疏血通注射液联合长春西汀治疗急性脑梗死临床价值 　　摘要：目的 分析疏血通注射液联合长春西汀治疗急性脑梗死的临床效果。方法 以我院2012年1月~12月应用疏血通注射液治疗的83例急性脑梗死患者为对照组，以我院同期加用长春西汀治疗的83例患者为联合组，对比两组患者疗总有效率及神经功能缺损、日常生活能力评分情况，以评定其疗效。结果 联合组治疗总有效率显著高于对照组，神经功能缺损评分显著低于对照组，日常生活能力评分显著高于对照组，两组各项数据经比较差异具有统计学意义，（P0.01）。不良反应发生率与对照组相当。结论 应用疏血通注射液联合长春西汀治疗急性脑梗死，患者症状改善显著，安全可靠，值得临床推广应用。 　　关键词：长春西汀；急性脑梗死；疏血通注射液 　　Analysis of Shuxuetong Injection Combined with Changchun Fluoxetine in the Treatment of Acute Cerebral Infarction Effect 　　WANG Ying-ju 　　(Hongjiang City Peoples Hospital,Hongjiang 418116,Hunan,China) 　　Abstract：ObjectiveTo analyze Shuxuetong joint vinpocetine injection for treatment of acute cerebral infarction. MethodsFrom January 2012 - December Shuxuetong injection treatment as control group, 83 cases of acute cerebral infarction patients in our hospital during the same period and 83 patients treated with vinpocetine for joint group, compared two groups of treatment in patients with total effective rate and neurologic deficits and daily life ability to score, to assess their effectiveness. ResultsThe combined treatment group total effective rate is significantly higher than the control group, the neural function defect score was significantly lower than the control group, daily life ability score is significantly higher than the control group, two groups of data by comparing differences statistically significant, (P 0.01). Incidence of adverse reactions and the control group. ConclusionThe application of combined vinpocetine Shuxuetong injection in treatment of acute cerebral infarction, patients with symptoms improved significantly, safe and reliable, worthy of clinical popularization and application. 　　Key words：Vinpocetine;Acute cerebral infarction;Shuxuetong injection 　　 　　急性脑梗死多因为血管内皮功能受损、血小板黏附于局部并聚集、胶原纤维暴露等原因形成血栓斑块，引发栓塞，血液流通不畅导致梗死，造成代谢性酸中毒，发生不可逆损害，周围缺血半暗带神经细胞部分受损，导致了继发性神经细胞坏死和凋亡，急性脑梗死救治的关键在于抢救缺血半暗带、尽早开通血管、减轻再灌注损伤、抑制血小板聚集、恢复梗死区血供和缩小心肌梗死范围[1]。我院在征得患者同意后对2012年1月~12月收治的部分急性脑梗死患者联合应用疏血通注射液和长春西汀进行治疗，取得了较好的效果，现报道如下。 　　1资料与方法