阿卡波糖片对老年急性心肌梗死患者心室重构影响.docVIP

阿卡波糖片对老年急性心肌梗死患者心室重构影响 　　【摘要】 目的：分析阿卡波糖片??老年急性心肌梗死患者心室重构的影响。方法：选取2014年 　　10月-2016年10月本院收治的老年急性心肌梗死疾病患者92例作为研究对象，按照随机数字法分为对照组和治疗组，每组各46例。对照组采用常规抗心肌梗死用药方案，治疗组在对照组基础上加用阿卡波糖片。比较用药前后左心室射血分数、梗死面积、心房钠尿肽、TNF-α等相关指标水平的改善幅度、老年急性心肌梗死药物治疗总有效率、用药期间出现的心室重构例数、心肌功能恢复正常时间和用药总时间、药物不良反应率。结果：治疗组在用药前后左心室射血分数、梗死面积、心房钠尿肽、TNF-α等相关指标水平的改善幅度均显著高于对照组，比较差异均有统计学意义（P0.05）；治疗组老年急性心肌梗死药物治疗总有效率为91.3%，高于对照组的71.7%，比较差异有统计学意义（P0.05）；用药期间，治疗组心室重构出现3例，少于对照组的11例，比较差异有统计学意义（P0.05）；心肌功能恢复正常时间和用药总时间均少于对照组，比较差异均有统计学意义（P0.05）；治疗组药物不良反应率为4.3%，显著低于对照组的21.7%，比较差异有统计学意义（P0.05）。结论：老年急性心肌梗死疾病患者采用阿卡波糖片进行治疗，可以有效控制心室重构现象的发生，大幅度改善心肌功能，缩短用药时间。 　　【关键词】 老年； 急性心肌梗死； 阿卡波糖片； 心室重构； 效果 　　【Abstract】 Objective：To analyze the Acarbose Tablet effect on ventricular remodeling in elderly patients with acute myocardial infarction patients disease with the clinical effect of treatment for Acarbose Tablet.Method：From October 2014 to October 2016 in our hospital，92 elderly patients with acute myocardial infarction in our hospital were selected as research objects，they were divided into control group and treatment group according to the random number table method，46 cases in each group.The control group was treated with conventional anti myocardial infarction therapy，the treatment group was given Acarbose Tablet based on the control group.The left ventricular ejection fraction，infarct size，atrial natriuretic peptide，TNF-α and other related indicators of the levels improvement，the elderly patients with acute myocardial infarction treatment，the total efficiency of treatment during ventricular remodeling cases，myocardial function recovery time and total treatment time，adverse drug reaction rate of two groups were compared before and after treatment.Result：The patients in the treatment group before and after treatment，left ventricular ejection fraction，infarct size，atrial natriuretic peptide，TNF-α and other related indicators of the levels improvement were better than these of the control group，the differences were statistically signifi