基础医学课件-connective tissue.pptVIP

Connective tissue General featuressmall number of cells and large amount of extracellular ground substanceno polarityvascularizedoriginate from mesenchyme（间充质）-embryonic CTFunction: connection, supporting, protecting, nutrition, defence and repairing Mesenchyme（间充质）---mesenchymal cell: Structure:stellate in shaped with processesa large nucleus,with clear nucleolusslight basophilic cytoplasm Function: undifferentiated cell multiple developmental potential →CT cell, SM and endothelial cell---matrix Classification ---CT in narrow sense means connetive tissue proper （固有结缔组织）which include loose CT, dense CT, adipose T and reticular tissue ---CT in wide sense includes cartilage(软骨), bone and blood cartilage boneblood Features: more types of cells, less fibersFunctions: connection, supporting, defence and repairingconsists of cells, fiber and ground substanceLoose connective tissue （疏松结缔组织） (areolar tissue) Fibers1. Collagenous fibers（胶原纤维）2. Elastic fibers（弹性纤维）3. Reticular fibers（网状纤维）  LM: 1-20 um in diameterBelt-liked wave and branch to form a networkEosinophilicCollagenous fiber（胶原纤维） (white fiber) EM: parallel-arranged fibrilsFibril（原纤维）: 20-200nm in diameterHave periodic cross striation at 64-70nm interval LM: thinner and less, 0.2-1.0 umSlight red (HE) branch and form a network EM: core: elastin-low electron densityPeripheral: microfibril (微原纤维)10-12 nm, electron dense ↑ fibrillin(原纤维蛋白)Elastic fiber （弹性纤维）(yellow fiber) LM: thin and less,0.2-1.0 um in diameter, branch to form networkArgyrophilic fiber (silver impregnation method)EM: type III collagen64nm cross striationDistribution: reticular tissueconnecting portion, e.g.reticular laminaReticular fiber（网状纤维） Ground substance（基质）---amorphous colloidal substance---consists of proteoglycan（蛋白多糖）, glycoprotein（糖蛋白） and tissue fluid ①Proteoglycan（蛋白多糖）-large molecular complex---glycosaminoglycans（糖胺多糖）chondroitin s