Metoprolol treatment of angina pectoris on the clinical observation.docVIP

 PAGE \* MERGEFORMAT 3 Metoprolol treatment of angina pectoris on the clinical observation 1 Materials and Methods 1.1 General information on all the cases were elderly patients in our hospital. 62 patients were randomly divided into two groups, metoprolol in 38 patients, including 33 males and 5 females, aged 60 to 82 years, average 65.8 years old. the control group 24 patients, 19 males and 5 females, aged 58 to 72 years, mean 61.3 years old. 1.2 treatment group were given metoprolol 50 mg to 100 mg metoprolol and conventional drugs crown expansion, expansion of the control group only received conventional crown drugs. Two groups of conventional drug formulations crown expansion, the same dose and route of administration. Both groups were continuously observed for 4 weeks. Electrocardiogram 1 week review. 1.3 The evaluation standard markedly: symptoms of angina, ECG returned to normal by the ischemic changes, effective: angina pectoris symptom relief or reduction in the number of pain, ECG ST segment depression after treatment, recovery 0.05mv more, or the main lead Measurement of T wave shoaling together more than 50%, is invalid: no relief of clinical symptoms of angina and ECG did not change. 2 Results Symptom improvement in angina pectoris, the metoprolol group was 92%, significantly higher than 71.5% in group P lt;0.05, ECG metoprolol group than the control group, There was a significant difference P lt;0.05. Metoprolol treatment heart rate, blood pressure, while the control group did not change significantly. 3 Discussion Metoprolol blood pressure by reducing the tension of the cardiac ejection resistance, reducing myocardial oxygen consumption and prevention of angina, improve the result of insufficient oxygen and myocardial energy metabolism and abnormal electrical activity of the heart. Some scholars believe that because the current to alleviate angina myocardial oxygen supply and demand imbalances, not