Metronidazole concurrent chemotherapy combined with lidocaine gargle Effect of oral ulcers.doc

 PAGE \* MERGEFORMAT 9 Metronidazole concurrent chemotherapy combined with lidocaine gargle Effect of oral ulcers [Abstract] Objective To observe metronidazole concurrent chemotherapy combined with lidocaine gargle oral ulcers. Methods 62 cases of chemotherapy concurrent oral ulcers were randomly divided into 32 cases, 30 cases of the control group. In the other treatment and care program under the same conditions, the observation group were treated with metronidazole and lidocaine gargle gargle 3 times a day, every 10 ~ 20 ml, rinse time of 5 ~ 10 min, the control group according to the traditional oral care requirements .7 days in nursing two groups were compared in the treatment of oral ulcers. Results of oral ulcers in patients observed total effective rate was 96.88%, significantly higher than the 66.67%, the two groups was statistically significant (P lt;0.01 ). Conclusions metronidazole concurrent chemotherapy combined with lidocaine gargle good effect of oral ulcers, especially in pain relief has a good effect, to ensure the smooth progress of chemotherapy and improve patients quality of life. [Keywords:] cancer chemotherapy; oral ulcers; gargle; Oral Care Chemotherapy (referred to as chemotherapy) is an application of special chemicals to kill cancer cells or tissues of the treatment of patients with advanced cancer is often an important means of comprehensive treatment. But the lack of cell specificity, chemotherapy drugs in killing tumor cells while normal cells also produce toxic side effects, chemotherapy drugs on the direct stimulation of oral mucous membrane and epithelial cell injury can lead to ulceration [1], has been reported in the process of receiving conventional chemotherapy mucositis was 75% [2], concurrent oral ulcers, infection rate was 66% [3]. oral ulcer pain can seriously affect people’s eating, sleeping, etc., not only increase the suffering of patients, but also worsen malnutrition, and treatment of cancer quality of life