氯吡格雷与阿司匹林对进展性缺血性脑卒中患者神经功能血清hsCRP水平及预后影响.docVIP

氯吡格雷与阿司匹林对进展性缺血性脑卒中患者神经功能血清hsCRP水平及预后影响 　　[摘要] 目的 探?氯吡格雷与阿司匹林对进展性缺血性脑卒中患者神经功能、血清hsCRP水平及预后的影响。 方法 采用回顾性方法，方便选取该院2015年11月―2017年1月以来收治的60例进展性缺血性脑卒中患者的临床资料，按照治疗方法的不同分为对照组及观察组，两组各30例，对照组给予阿司匹林治疗，观察组给予阿司匹林联合氯吡格雷治疗，比较两组患者的临床疗效经功能、血清hsCRP水平。 结果 观察组临床疗效96.67%（29/30）明显高于对照组临床疗效73.33%（22/30），差异有统计学意义（P0.05）；观察组在呼吸系统、循环系统和性功能系统整体水平上明显高于对照组，差异有统计学意义（P0.05）； 观察组血清hsCRP与血脂的整体水平明显优于对照组，差异有统计学意义（P0.05）。 结论 氯吡格雷与阿司匹林对进展性缺血性脑卒中患者临床疗效确切，不仅可以改善患者神经功能，进展性缺血性脑卒中患者的炎性水平有很好的降解作用，预后归转良好，值得临床实施应用。 　　[关键词] 氯吡格雷；阿司匹林；进展性缺血性脑卒中；神经功能；血清hsCRP水平；预后 　　[中图分类号] R972 [文献标识码] A [文章编号] 1674-0742（2017）10（c）-0124-03 　　Effects of Clopidogrel and Aspirin on Neurological Function， Serum hsCRP Level and Prognosis in Patients with Progressive Ischemic Stroke 　　LI Chun-shuang， FEI Ke-xin， SONG Yang， LIU Ping， WANG Xi-juan 　　Emergency Ward， Daqing Longnan Hospital of Heilongjiang Province， Daqing， Heilongjiang Province， 163453 China 　　[Abstract] Objective This paper tries to investigate the effects of clopidogrel and aspirin on neurological function， serum hsCRP level and prognosis in patients with progressive ischemic stroke. Methods The clinical data of 60 cases of patients with ischemic stroke treated in this hospital from November 2015 to January 2017 were retrospectively analyzed and were convenient divided into the control group and the observation group， with 30 cases in each group. The control group was given aspirin treatment， the observation group was given aspirin combined with clopidogrel treatment， the efficacy， function， the serum level of hsCRP were compared of two groups. Results The clinical curative effect of the observation group was 96.67%（29/30）， significantly higher than the control group of 73.33%（22/30）， with statistical significance（P0.05）； the observation group in the overall level of the respiratory system， circulatory system and function system were significantly higher than the control group， the difference was statistically significant（P0.05）； the observation group was signi