生殖道感染与宫颈癌前病变及宫颈癌相关性分析.docVIP

生殖道感染与宫颈癌前病变及宫颈癌相关性分析 　　【摘要】 目的 探讨生殖道感染与宫颈癌前病变、宫颈癌的相关性及危险因素分析。方法 对294例宫颈癌及癌前病变患者进行人乳头瘤病毒(HPV)、衣原体(CT)、BV、滴虫等病原体的检测,观察分析生殖道病原体与宫颈癌前病变及宫颈癌的相关性。结果 人乳头瘤病毒(HPV)感染检出率明显升高,与对照组相比差异显著(P0.05),人乳头瘤病毒(HPV)感染与宫颈癌前病变(CIN)、宫颈癌的发生发展有明显相关性;衣原体、BV、滴虫感染率较高,与对照组相比亦存在显著差异(P0.05),衣原体、BV、滴虫感染与CIN、宫颈癌的发生发展有一定的相关危险性。结论 生殖道不同病原体感染与宫颈癌前病变及宫颈癌存在必然或一定的相关性,其相互作用的机制值得进一步探讨。? 　　【关键词】生殖道感染;癌前病变;宫颈癌;相关性? 　　【Abstract】 Objective Of reproductive tract infections and cervical precancerous lesions, cervical cancer and risk factors associated.Methods Pairs of 294 cases of cervical cancer and precancerous lesions in patients with human papillomavirus (HPV), chlamydia (CT), BV, trichomoniasis and other pathogens, Observing and analyzing the reproductive tract pathogens and cervical precancerous lesions and cervical cancer correlation.Results Human papillomavirus (HPV) infection detection rate was significantly higher, compared with control group significant difference (P0.05), human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN), the occurrence and development of cervical cancer There was an obvious ; Chlamydia, BV, trichomoniasis infection rate higher, as compared with the control group there is also significant difference (P0.05), chlamydia, BV, trichomoniasis infection and CIN, cervical cancer occurrence and development of a certain degree of associated risk of Conclusion Reproductive tract of different pathogen infection and cervical cancer and precancerous lesions or cervical cancer there is bound to a certain degree of relevance, its mechanism of interaction is worth further exploration.? 　　【Key words】 Reproductive tract infection; Precancerous lesions; Cervical cancer; Correlation 　　 　　作者单位:276000山东省临沂市妇幼保健院宫颈科 　　 　　生殖道感染(reproductive tract infection,RTI)是威胁女性身心健康的重要疾病,尤其是生殖道人乳头瘤病毒(HPV)感染,近年已成为影响女性生殖健康的妇科常见疾病之一。宫颈癌的病因学研究已经确认,高危型人乳头瘤病毒(HPV)的生殖道感染为宫颈癌和癌前病变的重要相关因素[1,2],其次为衣原体(CT),细菌性阴道病(BV)、滴虫等。因生殖道感染人群的上升,育龄妇女的宫颈癌及癌前病变的发生率也在上升[3]。为进一步探讨生殖道感染与宫颈癌前病变(CIN)、宫颈癌的相关性,本文