非淋菌性尿道炎患者衣原体、支原体检测与药敏分析.pdfVIP

1894 实用预防医学 2007年12月 第14卷 第6期 Practical Preventive Medicine，Dec． 2007，Vol 14，No．6 文章编号：1006—3110(2007)06—1894—03 非淋菌性尿道炎患者衣原体、支原体检测与药敏分析 段 贞，陈 玮，李 浩，蔡瑞芸 摘要： 目的 了解可疑非淋菌性尿道炎(NGU)患者泌尿生殖道分泌物衣原体、支原体感染及药敏情况。 方法 应用衣原体试剂盒(胶体金法)定性检测衣原体抗原，支原体培养及药敏选用支原体药敏试剂盒，并对10种抗生素对支 原体的敏感性进行了分析。 结果 2 034例可疑NGU患者检出各种病原体感染765例，阳性率 37．6％，其中衣原体阳 性者384例(18．9％)，支原体阳性者324例(15．9％)，混合感染者57例(2．8％)。381例支原体对 10种抗生素的敏感率 最高的是交沙霉素和强力霉素(89．76％、88．45％)，其次为克拉霉素(69．55％)，耐药率最高的是环丙沙星(93．44％)，其 次为红霉素(64．31％)和可乐必妥(56．96％)。 结论 诊治NGU患者感染，应进行衣原体、支原体检测和药敏试验，选 择敏感有效的抗生素，控制NGU的传播和蔓延。 关键词： 非淋菌性尿道炎；衣原体；支原体；药敏试验 中图分类号：R691．3 文献标识码：A Analysis of Detection and Susceptibility Results for Chlamydia and Mycoplusma Strains From Non——gonococcus Urethritis Pa- tients DUAN Zhen，CHEN Wei，LI Hao，et a1．(Hunan Provincial People’S Hospital，Changsha 410005，Hunan，Chi- na) Abstract： Objective To investigate chlamydozoan and mycoplasma in urogenital tract infection and their susceptibili- ties to antibiotics in suspected non—gonococcus urethritis(NGU)patients． Methods Chlamydozoan antigen was qualita— tively determined using colloidal gold technique．Mycoplasma culture and drug susceptibility were carried out with mycoplasma drug sensitivity kit，and the sensitivity of 10 kinds of antibiotics to mycoplasma was analyzed． Results Among the 2，034 patients suspected with NGU，765 were positive with various pathogens，and the positive rate was 37．6％ ．The positive rates of chlamydozoan，mycoplasma and mixed both infection were 384，324，and 57 respectively．Among the 38 1 mycoplasma in- fection cases，the sensitive antibiotics were josamycine(89．76％)，doxycycline(88．45％)，and clarithromycine(69．55％)； however，mycoplasma was not sensitive to ciprofloxacin(93．44％)，erythromycin(64．3 1％)and cravit(56．96％)． Con- clusions Diagnosis of NGU patient s