肺气虚弱型及肺经伏热型变应性鼻炎与血清IL-2、IL-13相关性研究中医五官科学专业论文.docxVIP

成都中医药大学硕士学位论文 成都中医药大学硕士学位论文 PAGE PAGE 10 Abstract Objective: To explore the effect of interleukin-2(IL-2) and interleukin-13(IL-13) in allergic rhinitis(AR) and to provied evidences for AR and its typing in TCM. Data and methods: According to the standards of Lanzhou and differentiation of symptoms and sings in TCM , fifty-five cases with AR were selected ,inclding 20 males and 35 females . The patients average age was(34.23士1.657) years, including 28 cases of insufficiency of lung-QI, 27 cases of lung meridian latent pyrexia. The normal control group contained twenty-nine people (11 males and 18 females), whose average age was(30.79±2.106) years. The levels of IL-2 and IL-13 in peripheral blood of the research object were measured with enzyme linked immunosorbent assay (ELISA). Then data in groups were analysed. Results:① It showed that the local signs of the tow TCM symtom types were different . The group of insufficiency of lung-QI had the severe appearance of nasal mucosal edema. And the nasal mucosa of the group with lung meridian latent pyrexia was much more red than the other, the differenes had statistical significance(P0.05). ②The level of IL-13 in the tow experimental groups was increased significantly compared with the nomal control(P0.05) . However, there was no statistical significance between the two experimental groups(P0.05). And the level of IL-2 decreased significantly in the patients groups compared with the nomal control(P0.05) . And the level of IL-2 in the group of lung meridian latent pyrexia was decreased significantly compared with the insufficiency of lung-QI group(P0.05).The ratio of IL-2 and IL-13(IL-2/IL-13) decreased significantly in the patients groups compared with the nomal control(P0.05) .In which the level of the lung meridian latent pyrexia group was the lowest , and the differenes between the two Syndrome Type of TCM had statistical significance(P0.0